João T Barata Selected Research

Interleukin-7 Receptors (Interleukin 7 Receptor)

1/2022	Mutant IL7R collaborates with MYC to induce T-cell acute lymphoblastic leukemia.
11/2018	STAT5 is essential for IL-7-mediated viability, growth, and proliferation of T-cell acute lymphoblastic leukemia cells.
11/2016	Optimal interleukin-7 receptor-mediated signaling, cell cycle progression and viability of T-cell acute lymphoblastic leukemia cells rely on casein kinase 2 activity.
7/2011	IL-7 contributes to the progression of human T-cell acute lymphoblastic leukemias.

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João T Barata Research Topics

Disease

25	Leukemia 01/2022 - 05/2009
20	Neoplasms (Cancer) 01/2022 - 05/2009
20	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2022 - 04/2010
16	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2022 - 04/2010
3	Lymphoma (Lymphomas) 01/2020 - 03/2010
3	Carcinogenesis 12/2019 - 08/2007
2	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2014 - 10/2011
1	Neoplasm Metastasis (Metastasis) 01/2022
1	Thymus Hyperplasia 01/2021
1	Hematologic Neoplasms (Hematological Malignancy) 01/2020
1	Residual Neoplasm 01/2020
1	Lymphoid Leukemia 01/2019
1	B-Cell Lymphoma (Lymphoma, B Cell) 11/2016
1	Thymoma (Thymic Carcinoma) 11/2016
1	Disease Progression 01/2016
1	Adenocarcinoma 02/2015
1	T-Cell Leukemia (Leukemia, T Cell) 07/2011

Drug/Important Bio-Agent (IBA)

14	Interleukin-7 (Interleukin 7)IBA 01/2022 - 07/2011
5	Proteins (Proteins, Gene)FDA Link 02/2016 - 08/2007
4	Phosphotransferases (Kinase)IBA 01/2022 - 06/2014
4	Interleukin-7 Receptors (Interleukin 7 Receptor)IBA 01/2022 - 07/2011
4	CytokinesIBA 05/2020 - 07/2011
4	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 05/2020 - 11/2016
4	Phosphoric Monoester Hydrolases (Phosphatases)IBA 05/2020 - 01/2014
3	TensinsIBA 05/2020 - 01/2014
3	Casein Kinase II (Casein Kinase 2)IBA 05/2020 - 10/2010
3	MicroRNAs (MicroRNA)IBA 12/2019 - 01/2016
2	Biological ProductsIBA 01/2021 - 10/2017
2	Peptides (Polypeptides)IBA 05/2020 - 01/2014
2	CIGB-300IBA 05/2020 - 01/2014
2	GlucocorticoidsIBA 01/2020 - 03/2018
2	Dexamethasone (Maxidex)FDA LinkGeneric 01/2019 - 03/2018
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2019 - 05/2009
2	Sirolimus (Rapamycin)FDA Link 11/2018 - 04/2011
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 11/2018 - 10/2011
2	Protein Isoforms (Isoforms)IBA 03/2018 - 08/2007
2	LipidsIBA 02/2015 - 06/2014
2	PTEN Phosphohydrolase (PTEN Phosphatase)IBA 06/2014 - 04/2010
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 09/2011 - 04/2010
2	Biomarkers (Surrogate Marker)IBA 08/2010 - 03/2010
2	AntigensIBA 08/2010 - 05/2009
1	Lactate Dehydrogenase 5IBA 01/2022
1	AZD1208IBA 01/2021
1	Tetracycline (Achromycin)FDA LinkGeneric 01/2021
1	Messenger RNA (mRNA)IBA 01/2021
1	ruxolitinibIBA 01/2021
1	dactolisibIBA 01/2021
1	palbociclibIBA 01/2021
1	venetoclaxIBA 01/2021
1	NucleophosminIBA 05/2020
1	Janus KinasesIBA 05/2020
1	Lymphoid Enhancer-Binding Factor 1IBA 01/2020
1	Immunoconjugates (Immunoconjugate)IBA 01/2019
1	RNA (Ribonucleic Acid)IBA 11/2018
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 11/2018
1	ChromatinIBA 11/2018
1	Protein Kinases (Protein Kinase)IBA 11/2016
1	STAT5 Transcription FactorIBA 11/2016
1	T-Cell Acute Lymphocytic Leukemia Protein 1IBA 02/2016
1	Transcription Factors (Transcription Factor)IBA 01/2016
1	Lymphotoxin-alpha (Lymphotoxin)IBA 12/2015
1	Adenosine Monophosphate (AMP)IBA 02/2015
1	human neutrophil peptide 1IBA 02/2015
1	Pharmaceutical PreparationsIBA 02/2015
1	silmitasertibIBA 06/2014
1	DisulfidesIBA 05/2013
1	Therapeutic UsesIBA 07/2011
1	temsirolimus FDA Link 04/2011
1	Cyclin-Dependent Kinase Inhibitor p27IBA 04/2011
1	Eukaryotic Initiation Factor-4G (Eukaryotic Initiation Factor 4G)IBA 04/2011
1	TOR Serine-Threonine KinasesIBA 04/2011
1	Ribosomal Proteins (Ribosomal Protein)IBA 04/2011
1	Membrane Proteins (Integral Membrane Proteins)IBA 08/2010
1	Complementary DNA (cDNA)IBA 08/2010
1	2'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA 04/2010
1	Gamma Secretase Inhibitors and ModulatorsIBA 04/2010
1	Dichlororibofuranosylbenzimidazole (DRB)IBA 04/2010
1	HLA Antigens (Human Leukocyte Antigens)IBA 03/2010
1	4-hydroxy-3-methyl-2-butenyl diphosphateIBA 05/2009
1	4-hydroxy-3-methylbut-2-enyl pyrophosphateIBA 05/2009
1	prenylIBA 05/2009
1	diphosphoric acid (pyrophosphoric acid)IBA 05/2009
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2007

Therapy/Procedure

7	Therapeutics 01/2022 - 10/2011
4	Drug Therapy (Chemotherapy) 01/2020 - 09/2014
4	Immunotherapy 05/2013 - 05/2009
2	Transplantation 01/2021 - 05/2009
1	Cell Transplantation 01/2022
1	Induction Chemotherapy 01/2020
1	Combination Drug Therapy (Combination Chemotherapy) 03/2018
1	Heterologous Transplantation (Xenotransplantation) 07/2014